1
累积的DNA损伤是斑马鱼睡眠的原因
2
Parp1调控清除神经元DNA损伤
3
Parp1的敲除影响睡眠质量
研究结果
1
内源因素
2
外源因素
End
参考资料:
[3]Hoeijmakers JH. DNA damage, aging, and cancer. N Engl JMed. 2009 Oct 8;361(15):1475-85. doi: 10.1056/NEJMra0804615. Erratum in: N EnglJ Med. 2009 Nov 5;361(19):1914. PMID: 19812404.
[4]Shi L, Oberdoerffer P. Chromatin dynamics in DNA double-strand break repair. Biochim Biophys Acta. 2012 Jul;1819(7):811-9. doi:10.1016/j.bbagrm.2012.01.002. Epub 2012 Jan 17. PMID: 22285574; PMCID:PMC3368990.
[5]Chapman JR, Taylor MR, Boulton SJ. Playing the end game: DNA double-strand break repair pathway choice. Mol Cell. 2012 Aug24;47(4):497-510. doi: 10.1016/j.molcel.2012.07.029. PMID: 22920291.
[6]Helena JM, Joubert AM, Grobbelaar S, et al. Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes. Int J Mol Sci. 2018 Apr11;19(4):1148. doi: 10.3390/ijms19041148. PMID: 29641431; PMCID: PMC5979424.
[7]Dedon PC, Plastaras JP, Rouzer CA, et al. Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal. Proc Natl Acad Sci U S A. 1998 Sep15;95(19):11113-6. doi: 10.1073/pnas.95.19.11113. PMID: 9736698; PMCID:PMC21604.
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